We would like to congratulate Dr. Roberto Araya, Associate Professor, Department of Neurosciences, University of Montreal on the recent publication in the January 2. 2023 issue of the prestigious journal Proceedings of the National Academy of Sciences. The article entitled Altered integration of excitatory inputs onto the basal dendrites of layer 5 pyramidal neurons in a mouse model of Fragile X syndrome. This work funded in part by the Scottish Rite Charitable Foundation shows how in Fragile X syndrome (FXS), the most common cause of autism, sensory signals from the outside world are integrated differently, causing them to be underrepresented by cortical pyramidal neurons in the brain. This phenomenon could provide important clues to the underlying cause of the symptoms of this syndrome. The research team’s work not only provides insight into the mechanism at the cellular level, but also opens the door to new targets for therapeutic strategies.